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Invitrogen
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Immunogen sequence: PGVCKVSTDL LREGAPIEPD PPVSHWKPEA VQYYEDGARI EAAFRNYIHR ADARQEEDSY EIFICHANVI RYIVCSIPP
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。