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Abnova
PHF15 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00023338-B02P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PHF15 (AAH04292.1, 1 a.a. approximately 246 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAMSEWPLNN GHREDPAPGL LSEELLQDEE TLLSFMRDPS LRPGDPARKA RGRTRLPAKK KPPPPPPQDG PGSRTTPDKA PKKTWGQDAG SGKGGQGPPT RKPPRRTSSH LPSSPAAGDC PILATPESPP PLAPETPDEA ASVAADSDVQ VPGPAASPKP LGRLRPPRES KVTRRLPGAR PDAGMGPPSA VAERPKISLH FDTETDGYFS DGEMSDSDVE AEDGGVQRGP REAGAEEVVR MGVLAS
靶标信息
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (PubMed:16387653). Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020). Also acts as a ubiquitin ligase E3 toward itself. Positive regulator of neurogenesis. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: jade family PHD finger protein 2; KIAA0239; PHD finger protein 15; unnamed protein product
基因别名: JADE-2; PHF15
UniProt ID: (Human) Q9NQC1
Entrez Gene ID: (Human) 23338
protein binding
histone acetyltransferase activity (H3-K14 specific)
histone acetyltransferase activity (H4-K5 specific)
histone acetyltransferase activity (H4-K8 specific)
histone acetyltransferase activity (H4-K12 specific)
histone acetyltransferase activity (H4-K16 specific)
ubiquitin protein ligase activity
histone reader activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
