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Abnova
PHLDA1 Polyclonal Antibody, MaxPab™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00022822-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PHLDA1 (AAH18929.3, 1 a.a. approximately 259 a.a) full-length human protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.54 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLESSGCKAL KEGVLEKRSD GLLQLWKKKC CILTEEGLLL IPPKQLQHQQ QQQQQQQQQQ QQPGQGPAEP SQPSGPAVAS LEPPVKLKEL HFSNMKTVDC VERKGKYMYF TVVMAEGKEI DFRCPQDQGW NAEITLQMVQ YKNRQAILAV KSTRQKQQHL VQQQPPSQPQ PQPQLQPQPQ PQPQPQPQPQ SQPQPQPQPK PQPQQLHPYP HPHPHPHSHP HSHPHPHPHP HPHQIPHPHP QPHSQPHGHR LLRSTSNSA
靶标信息
Cytotoxic T lymphocyte (CTL)-mediated cytotoxicity constitutes an important component of specific effector mechanisms in immunosurveillance against virus-infected or -transformed cells. Two mechanisms appear to account for this activity, one of which is the perforin-based process. Independently, a FAS-based mechanism involves the transducing molecule FAS (APO-1) and its ligand (FAS-L). The human FAS (APO-1) protein is a 48 kDa cell surface glycoprotein that belongs to a family of receptors that includes CD40, nerve growth factor receptors and tumor necrosis factor receptors. The FAS antigen is expressed on a broad range of lymphoid cell lines, and is expressed at high levels in T cells subsequent to crosslinking of the T cell receptor (TCR). A previously undescribed protein, TDAG51, restores activation- induced apoptosis in cells that have lost the ability to display Fas in response to activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptosis-associated nuclear protein; PQ-rich protein; PQR protein; proline- and glutamine-rich protein; proline- and histidine-rich protein; proline-histidine rich protein; proline-histidine rich protein PHRIP; T-cell death-associated gene 51 protein; unnamed protein product
基因别名: DT1P1B11; PHRIP; TDAG51
UniProt ID: (Human) Q8WV24
Entrez Gene ID: (Human) 22822
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
