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Invitrogen
PHRF1 Polyclonal Antibody
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PHRF1 Antibody (PA5-116730) in WB
Western blot analysis of PHRF1 in extracts of various cell lines. Samples were incubated with PHRF1 Polyclonal antibody (Product # PA5-116730) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-116730
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1350-1450 of human PHRF1 (NP_0012735121)
偶联物
形式
Liquid
浓度
1.32 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Juakat, K-562, HepG2, HeLa
Immunogen sequence: KAEAPSSPDV APAGKEDSPS ASGRVQEAAR PEEVVSQTPL LRSRALVKRV TWNLQESESS APAEDRAPRA PLHRPQKPRE GAWDMEDVAP TGVRQVFSEL P
靶标信息
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CTD-binding SR-like protein rA9; PHD and RING finger domain-containing protein 1; protein phosphatase 1, regulatory subunit 125
基因别名: KIAA1542; PHRF1; PPP1R125; RNF221
UniProt ID: (Human) Q9P1Y6
Entrez Gene ID: (Human) 57661
