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Proteintech
PITX2 Polyclonal Antibody
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产品信息
11106-1-AP
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PITX2 Fusion Protein Ag1583 (1-286 aa encoded by BC013998)
偶联物
形式
Liquid
浓度
0.13 mg/mL
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MNCMKGPLH LEHRAAGTKL SAVSSSSCHH PQPLAMASVL APGQPRSLDS SKHRLEVHTI SDTSSPEAAE KDKSQQGKNE DVGAEDPSKK KRQRRQRTHF TSQQLQELEA TFQRNRYPDM STREEIAVWT NLTEARVRVW FKNRRAKWRK RERNQQAELC KNGFGPQFNG LMQPYDDMYP GYSYNNWAAK GLTSASLSTK SFPFFNSMNV NPLSSQSMFS PPNSISSMSM SSSMVPSAVT GVPGSSLNSL NNLNNLSSPS LNSAVPTPAC PYAPPTPPYV YRDTCNS (1-286 aa encoded by BC013998)
靶标信息
Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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