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Invitrogen
PJA2 Polyclonal Antibody
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PJA2 Antibody (PA5-35950) in IHC (P)
PJA2 Polyclonal Antibody detects PJA2 protein at membrane on mouse esophagus by immunohistochemical analysis. Sample: Paraffin-embedded mouse esophagus. PJA2 Polyclonal Antibody (Product # PA5-35950) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-35950
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the C-terminus region of human PJA2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Predicted reactivity: Human (99%), Mouse (99%), Rat (99%), Bovine (99%).
靶标信息
Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA-mediated long-term memory processes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E3 ubiquitin-protein ligase Praja-2; E3 ubiquitin-protein ligase Praja2; neurodegeneration associated protein 1; praja 2, RING-H2 motif containing; praja ring finger 2, E3 ubiquitin protein ligase; praja-2; Praja2; protein carrying the RING-H2 sequence motif; RING finger protein 131; RING-type E3 ubiquitin transferase Praja-2
基因别名: AI447901; AL022700; KIAA0438; mKIAA0438; Neurodap1; PJA2; RNF131
UniProt ID: (Human) O43164, (Mouse) Q80U04
Entrez Gene ID: (Human) 9867, (Mouse) 224938
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
protein kinase A catalytic subunit binding
protein kinase A regulatory subunit binding
ubiquitin protein ligase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
