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Proteintech
PLAG1 Polyclonal Antibody
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产品信息
18018-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLAG1 Fusion Protein Ag12566 (151-500 aa encoded by BC075047)
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: TCKVCLQTF ESTGVLLEHL KSHAGKSSGG VKEKKHQCEH CDRRFYTRKD VRRHMVVHTG RKDFLCQYCA QRFGRKDHLT RHMKKSHNQE LLKVKTEPVD FLDPFTCNVS VPIKDELLPV MSLPSSELLS KPFTNTLQLN LYNTPFQSMQ SSGSAHQMIT TLPLGMTCPI DMDTVHPSHH LSFKYPFSST SYAISIPEKE QPLKGEIESY LMELQGGVPS SSQDSQASSS SKLGLDPQIG SLDDGAGDLS LSKSSISISD PLNTPALDFS QLFNFIPLNG PPYNPLSVGS LGMSYSQEEA HSSVSQLPPQ TQDLQDPANT IGLGSLHSLS AAFTSSLSTS TTLPRFHQAF Q (151-500 aa encoded by BC075047)
靶标信息
Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C2H2 zinc finger protein PLAG1; COL1A2/PLAG1 fusion; HAS2/PLAG1 fusion; pleiomorphic adenoma gene 1; Pleiomorphic adenoma gene 1 protein; Zinc finger protein PLAG1
基因别名: PLAG1; PSA; SGPA; ZNF912
UniProt ID: (Human) Q6DJT9, (Rat) Q5U2T6, (Mouse) Q9QYE0
Entrez Gene ID: (Human) 5324, (Rat) 297804, (Mouse) 56711
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
metal ion binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
molecular_function
nucleic acid binding
DNA binding
C2H2 zinc finger transcription factor
transcription from RNA polymerase II promoter
negative regulation of gene expression
gland morphogenesis
multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glial cell proliferation
prostate gland growth
biological_process
positive regulation of gene expression
organ growth
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
