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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: DHCDRRFYT RKDVRRHLVV HTGRKDFLCQ YCAQRFGRKD HLTRHVKKSH SQELLKIKTE PVDMLGLLSC SSTVSVKEEL SPVLCMASRD VMGTKAFPGM LPMGMYGAHI PTMPSTGVPH SLVHNTLPMG MSYPLESSPI SSPAQLPPKY QLGSTSYLPD KLPKVEVDSF LAELPGSLSL SSAEPQPASP QPAAAAALLD EALLAKSPAN LSEALCAANV DFSHLLGFLP LNLPPCNPPG ATGGLVMGYS QAEAQPLLTT LQAQPQDSPG AGGPLNFGPL HSLPPVFTSG LSSTTLPRFH QAFQ (194-496 aa encoded by B C023655)
The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C2H2-type zinc finger protein; KIAA0198; pleiomorphic adenoma gene-like 2; pleiomorphic adenoma-like protein 2; pleomorphic adenoma gene like 2; unnamed protein product; zinc finger transcription factor
基因别名: mKIAA0198; ZNF900
UniProt ID: (Human) Q9UPG8
Entrez Gene ID: (Human) 5326, (Mouse) 54711