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Proteintech
PLCD3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
16792-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLCD3 Fusion Protein Ag10249 (441-789 aa encoded by BC072384)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.15 mg/mL
规格
22.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: AMARHLCTI LGDMLVTQAL DSPNPEELPS PEQLKGRVLV KGKKLPAARS EDGRALSDRE EEEEDDEEEE EEVEAAAQRR LAKQISPELS ALAVYCHATR LRTLHPAPNA PQPCQVSSLS ERKAKKLIRE AGNSFVRHNA RQLTRVYPLG LRMNSANYSP QEMWNSGCQL VALNFQTPGY EMDLNAGRFL VNGQCGYVLK PACLRQPDST FDPEYPGPPR TTLSIQVLTA QQLPKLNAEK PHSIVDPLVR IEIHGVPADC ARQETDYVLN NGFNPRWGQT LQFQLRAPEL ALVRFVVEDY DATSPNDFVG QFTLPLSSLK QGYRHIHLLS KDGASLSPAT LFIQIRIQRS (441-789 aa encoded by BC072384)
靶标信息
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; phosphoinositide phospholipase C-delta-3; PLC delta3; unnamed protein product
基因别名: PLC-delta-3
UniProt ID: (Human) Q8N3E9
Entrez Gene ID: (Human) 113026
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
