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Invitrogen
PLCD3 Polyclonal Antibody
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产品信息
PA5-55243
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human PLCD3
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: CDHSNNDRLE GAEIEEFLRR LLKRPELEEI FHQYSGEDRV LSAPELLEFL EDQGEEGATL ARAQQLIQTY ELNETAKQHE LMTLDGFMMY LL
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 91%.
靶标信息
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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