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Proteintech
PLEK Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
12506-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PLEK Fusion Protein Ag3187 (1-350 aa encoded by BC018549)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
30 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEPKRIREG YLVKKGSVFN TWKPMWVVLL EDGIEFYKKK SDNSPKGMIP LKGSTLTSPC QDFGKRMFVF KITTTKQQDH FFQAAFLEER DAWVRDIKKA IKCIEGGQKF ARKSTRRSIR LPETIDLGAL YLSMKDTEKG IKELNLEKDK KIFNHCFTGN CVIDWLVSNQ SVRNRQEGLM IASSLLNEGY LQPAGDMSKS AVDGTAENPF LDNPDAFYYF PDSGFFCEEN SSDDDVILKE EFRGVIIKQG CLLKQGHRRK NWKVRKFILR EDPAYLHYYD PAGAEDPLGA IHLRGCVVTS VESNSNGRKS EEENLFEIIT ADEVHYFLQA ATPKERTEWI KAIQMASRTG K (1-350 aa encoded by BC018549)
靶标信息
Major protein kinase C substrate of platelets.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: contains PH domain at both N and C terminus; major substrate of protein kinase C; FLJ27168; platelet 47 kDa protein; PLEK; unnamed protein product
基因别名: 2010300B13Rik; P47; PLEK1
UniProt ID: (Human) P08567, (Rat) Q4KM33, (Mouse) Q9JHK5
Entrez Gene ID: (Human) 5341, (Rat) 364206, (Mouse) 56193
hematopoietic progenitor cell differentiation
platelet degranulation
phospholipase C-activating G-protein coupled receptor signaling pathway
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
actin cytoskeleton organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
intracellular signal transduction
inositol phosphate metabolic process
positive regulation of cellular component biogenesis
negative regulation of G-protein coupled receptor protein signaling pathway
regulation of cell diameter
thrombin receptor signaling pathway
negative regulation of thrombin receptor signaling pathway
platelet aggregation
protein secretion by platelet
cell projection organization
negative regulation of calcium-mediated signaling
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
