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This target displays homology in the following species: Cow: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
PLEKHF2 may play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PH domain-containing family F member 2; Pleckstrin homology domain-containing family F member 2
Gene Aliases: 1110070J07Rik; AA673237; Plekhf2; ZFYVE18
UniProt ID: (Mouse) Q91WB4
Entrez Gene ID: (Mouse) 71801
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