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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GTQEVLCQLK RDQPSPCLSS AEDSGVDEGQ GSPSEMVHSS EFRVDNNHLL LLMIHVFREN EEQLFKMIRM STGHMEGNLQ LLYVLLTDCY VYLLRKGATE KPYLVEEAVS YNELDYVSV
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PH domain-containing family M member 2; Pleckstrin homology domain-containing family M member 2; RP11-169K16.1; Salmonella-induced filaments A and kinesin-interacting protein; SifA and kinesin-interacting protein
基因别名: KIAA0842; PLEKHM2; SKIP
Entrez Gene ID: (Human) 23207