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Invitrogen
PLLP Polyclonal Antibody
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产品信息
PA5-120398
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLLP (NP_057077.1).
偶联物
形式
Liquid
浓度
1.15 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: Mouse brain, Rat brain, Rat kidney. The target is usually found in the following locations: Membrane, Multi-pass membrane protein.
Immunogen sequence: MAEFPSKVST RTSSPAQGAE ASVSALRPDL GFVRSRLGAL MLLQLVLGLL VWALIADTPY HLYPAYGWVM FVAVFLWLVT IVLFNLYLFQ LHMKLYMVPW
靶标信息
Plasmolipin is an 18 kDa membrane-bound proteolipid that belongs to the tetraspan (4TM) family, a rapidly growing group of myelin-associated proteins. Many of these proteins could be linked to human hereditary demyelinating neuropathies. Studies indicate that plasmolipin is a component of the cytoskeletal structure and has been localized to the apical surface of tubular epithelial cells. It has been shown that, upon addition to lipid bilayers, plasmolipin induces formation of ion channels that are both voltage-dependent and potassium-specific. Plasmolipin was originally isolated from kidney tissue. Subsequently, it has been shown to be widely expressed, not only being present in kidney, but also in the nervous system, thymus, testis, lung, and thyroid gland.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Plasma membrane proteolipid; plasma membrane proteolipid (plasmolipin); Plasmolipin; transmembrane 4 superfamily member 11
基因别名: 0610010I06Rik; AV001002; Plapi; Pllp; Pmlp; Tm4sf11
UniProt ID: (Rat) P47987, (Mouse) Q9DCU2
Entrez Gene ID: (Rat) 64364, (Mouse) 67801
