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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody detects 215 and 195 kDa bands corresponding to the apparent molecular mass of Plexin D1 variants in human umbilical vein endothelial cells.
Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature. Mediates anti-angiogenic signaling in response to SEMA3E. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC75353; plexin family member; unnamed protein product
基因别名: 6230425C21Rik; b2b1863Clo; b2b553Clo; CHTD9; PLEXD1
UniProt ID: (Human) Q9Y4D7, (Mouse) Q3UH93
Entrez Gene ID: (Human) 23129, (Mouse) 67784, (Rat) 312652