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Invitrogen
PMCA ATPase Polyclonal Antibody
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图: 1 / 4
PMCA ATPase Antibody (PA5-114932) in ICC/IF
Immunocytochemistry analysis of PMCA ATPase in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-114932) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goa... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114932
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ATP2B4(Accession P23634), corresponding to amino acid residues K302-L352.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total Calcium Pump PMCA4 ATPase.
靶标信息
The calcium pump of the plasma membrane (PMCA ATPase) pumps calcium from the cytosol to the extracellular space. This membrane-bound enzyme is related to a number of other ATPases including the sarcoplasmic and endoplasmic reticulum calcium (SERCA) ATPase and the sodium/potassium pump. Studies indicate that there are four known isoforms of the PMCA ATPase which are encoded by a multigene family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATPase isoform 2 Na+K+ transporting beta polypeptide 2; ATPase isoform 2, Na+K+ transporting, beta polypeptide 2; deaf waddler; Matrix-remodeling-associated protein 1; plasma membrane Ca++-ATPase; plasma membrane Ca2+-ATPases 4; plasma membrane calcium ATPase; Plasma membrane calcium ATPase isoform 1; Plasma membrane calcium ATPase isoform 2; Plasma membrane calcium ATPase isoform 3; Plasma membrane calcium ATPase isoform 4; plasma membrane calcium pump; Plasma membrane calcium pump isoform 1; Plasma membrane calcium pump isoform 2; Plasma membrane calcium pump isoform 3; Plasma membrane calcium pump isoform 4; Plasma membrane calcium-transporting ATPase 1; Plasma membrane calcium-transporting ATPase 2; Plasma membrane calcium-transporting ATPase 3; Plasma membrane calcium-transporting ATPase 4; PMCA1; PMCA2; PMCA3; PMCA4; wriggle
基因别名: 2810442I22Rik; 6430519O13Rik; ATP2B1; ATP2B2; ATP2B3; ATP2B4; D6Abb2e; dfw; E130111D10Rik; Gena300; jog; MXRA1; PMCA1; Pmca1a; Pmca1b; Pmca1c; PMCA2; Pmca3; PMCA4; Tmy; wms; wri
UniProt ID: (Mouse) G5E829, (Rat) P11505, (Rat) P11506, (Mouse) Q9R0K7, (Rat) Q64568, (Rat) Q64542, (Mouse) Q6Q477
Entrez Gene ID: (Mouse) 67972, (Rat) 29598, (Rat) 24215, (Mouse) 11941, (Rat) 29599, (Mouse) 320707, (Rat) 29600, (Mouse) 381290
nucleotide binding
calcium-transporting ATPase activity
protein binding
calmodulin binding
ATP binding
hydrolase activity
PDZ domain binding
metal ion binding
calcium ion binding
protein C-terminus binding
calcium-dependent ATPase activity
acetylcholine receptor binding
glutamate receptor binding
sodium channel regulator activity
protein phosphatase 2B binding
nitric-oxide synthase inhibitor activity
nitric-oxide synthase binding
scaffold protein binding
primary active transporter
transport
ion transport
calcium ion transport
calcium ion transmembrane transport
calcium ion export
neural retina development
brain development
aging
metabolic process
response to cold
cellular response to vitamin D
cellular response to corticosterone stimulus
cell morphogenesis
cellular calcium ion homeostasis
organelle organization
lactation
sensory perception of sound
locomotory behavior
regulation of cell size
cerebellum development
cerebellar Purkinje cell layer morphogenesis
cerebellar Purkinje cell differentiation
cerebellar granule cell differentiation
neuron differentiation
locomotion
serotonin metabolic process
inner ear morphogenesis
otolith mineralization
cGMP metabolic process
regulation of synaptic plasticity
inner ear development
synapse organization
neuromuscular process controlling balance
detection of mechanical stimulus involved in sensory perception of sound
regulation of cytosolic calcium ion concentration
positive regulation of calcium ion transport
auditory receptor cell stereocilium organization
inner ear receptor cell differentiation
cochlea development
regulation of transcription from RNA polymerase II promoter
spermatogenesis
negative regulation of nitric oxide mediated signal transduction
hippocampus development
positive regulation of peptidyl-serine phosphorylation
negative regulation of nitric oxide biosynthetic process
negative regulation of nitric-oxide synthase activity
response to hydrostatic pressure
negative regulation of calcineurin-NFAT signaling cascade
cellular response to epinephrine stimulus
negative regulation of the force of heart contraction
negative regulation of arginine catabolic process
negative regulation of adrenergic receptor signaling pathway involved in heart process
negative regulation of cardiac muscle hypertrophy in response to stress
negative regulation of citrulline biosynthetic process
positive regulation of cAMP-dependent protein kinase activity
negative regulation of peptidyl-cysteine S-nitrosylation
regulation of sodium ion transmembrane transport
regulation of cell cycle G1/S phase transition
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