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Invitrogen
PNK Polyclonal Antibody
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PNK Antibody (PA1-29915) in WB
Western blot analysis of PNK in yeast extract (lane 1) and yeast extract + AD-PNK human fusion protein using a PNK polyclonal antibody (Product # PA1-29915) at a dilution of 1:1000 after incubation for 1hr in TBST. The AD fusion is an Activation Domain fusion protein. The band representing PNK is marked by the arrow.
产品信息
PA1-29915
产品规格
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence EPRLGRLYCQFSEG, from C Terminus of the protein sequence according to NP_009185.
偶联物
形式
Liquid
浓度
0.5 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
PA1-29915 detects PNK from human samples.
PA1-29915 has been successfully used in Western blot applications.
The PA1-29915 immunogen is: Peptide with sequence EPRLGRLYCQFSEG, from C Terminus of the protein sequence according to NP_009185.
靶标信息
Anti-human Polynucleotide Kinase Mouse Monoclonal Antibody recognizes polynucleotide kinase (PNK), a 57 kDa nuclear enzyme implicated in DNA strand repair processes that occur during DNA replication and recombination, or in response to DNA damaging agents. PNK targets the DNA 5'-hydroxy and 3'-phosphate termini for phosphorylation and dephosphorylation events. During strand breakage in human cells, normal PNK associates with other nuclear proteins to prepare the DNA termini for the enzymatic actions of DNA polymerase-beta and DNA ligase III. PNK is a key functional component in maintaining the genetic stability of human cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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