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Invitrogen
PNR Polyclonal Antibody
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产品信息
PA1-809
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-809 detects PNR from rat and human samples.
PA1-809 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~42 kDa protein representing PNR from rat tissue extracts.
The PA1-809 immunogen is a synthetic peptide corresponding to residues R(392) K T I G N T P M E K L L C D M F K N(410) of human PNR. This sequence is completely conserved between mouse and chicken. This immunizing peptide (cat. # PEP-237) can be used for neutralization and control experiments.
靶标信息
NR2E3, a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in NR2E3 results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in NR2E3 has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. NR2E3 is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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