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Invitrogen
POLG Polyclonal Antibody
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产品信息
PA1-21791
产品规格
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Purified native human recombinant amino acids 714 - 1061 DNA polymerase gamma.
偶联物
形式
Liquid
浓度
0.2 mg/mL
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
PA1-21791 detects DNA Polymerase gamma in Human samples.
PA1-21791 has been successfully used in and Western Blot procedures. Positive control of HeLa cells suggested.
PA1-21791 immunogen is purified native human recombinant amino acids 714 - 1061 DNA polymerase gamma.
靶标信息
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
