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POU2F3 Polyclonal Antibody
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POU2F3 Antibody (600-401-DR3) in ICC/IF
Immunofluorescence Microscopy of Rabbit anti-POU2F3 antibody. Tissue: rat brain. Primary antibody: POU2F3 antibody at 20 µg/mL. Secondary antibody: Fluorescein rabbit secondary antibody at 1:20,000. Localization: POU2F3 is nuclear. Staining: POU2F3 as red fluorescent signal.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
600-401-DR3
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-POU2F3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the C-terminus of human POU2F3.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
POU2F3 (POU class 2 homeobox 3) is a transcription factor that regulates gene expression by binding specific DNA sequences through its POU domain. It is best known for controlling the development and identity of tuft cells in epithelial tissues and has emerging roles in certain cancers, particularly tuft cell-like carcinomas.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: base pairs 945-995 correspond to helical domain 3 of the protein; oct-11; octamer-binding protein 11; octamer-binding transcription factor 11; OTF-11; POU domain transcription factor OCT11a; Rov 1 pou-homeodomain protein; Skn-1a, Epoc-1; transcription factor PLA-1; transcription factor Skn-1; unnamed protein product
基因别名: Epoc-1; OCT-11; Oct-11a; OCT11; OTF-11; Otf11; PLA-1; PLA1; Skin; Skin-1a; Skn-1a; Skn-li
UniProt ID: (Human) Q9UKI9, (Rat) P42571, (Mouse) P31362
Entrez Gene ID: (Human) 25833, (Rat) 116544, (Mouse) 18988
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
epidermis development
cell differentiation
keratinocyte differentiation
negative regulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
wound healing
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