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Proteintech
POU4F2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
55042-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.28 mg/mL
规格
42 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
靶标信息
POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons. POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: brain-3B; brain-specific homeobox/POU domain protein 3B; Brn-3-related POU transcription factor; Brn-3b; Brn3b POU domain transcription factor; POU domain protein; POU domain, class 4, transcription factor, related sequence 1; POU4F2; unnamed protein product
基因别名: Brn-3.2; Brn-3b; BRN3.2; BRN3B; mBrn3-3R; Pou4f-rs1
UniProt ID: (Human) Q12837, (Mouse) Q63934
Entrez Gene ID: (Human) 5458, (Mouse) 18997
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
p53 binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
promoter-specific chromatin binding
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
axon guidance
heart development
regulation of gene expression
positive regulation of cardiac muscle cell apoptotic process
neuron differentiation
intracellular estrogen receptor signaling pathway
cellular response to insulin stimulus
positive regulation of programmed cell death
negative regulation of cell differentiation
positive regulation of cell differentiation
positive regulation of osteoclast differentiation
positive regulation of axon extension
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glucose import
retina development in camera-type eye
cellular response to cytokine stimulus
cellular response to estradiol stimulus
cellular response to oxygen levels
intrinsic apoptotic signaling pathway by p53 class mediator
regulation of retinal ganglion cell axon guidance
negative regulation of amacrine cell differentiation
negative regulation of adipose tissue development
dorsal root ganglion development
positive regulation of transcription regulatory region DNA binding
apoptotic process
axonogenesis
sensory perception of sound
retinal ganglion cell axon guidance
axon extension
neuromuscular process controlling balance
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