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Invitrogen
POU4F2 Polyclonal Antibody
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产品信息
PA5-107007
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N terminal region of human POU4F2 (aa 1-51).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.4, with 2% sucrose
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 93%
靶标信息
POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons. POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Brain-3B; Brain-specific homeobox/POU domain protein 3B; Brn3b POU domain transcription factor; POU domain class 4 transcription factor 2; POU domain protein; POU domain, class 4, transcription factor 2
基因别名: Brn-3b; BRN3.2; BRN3B; POU4F2
UniProt ID: (Human) Q12837
Entrez Gene ID: (Human) 5458
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
negative regulation of transcription from RNA polymerase II promoter
MAPK cascade
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
spermatogenesis
axon guidance
sensory perception of sound
neuron differentiation
intracellular estrogen receptor signaling pathway
retinal ganglion cell axon guidance
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
axon extension
neuromuscular process controlling balance
retina development in camera-type eye
regulation of signal transduction by p53 class mediator
