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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
This antibody is predicted to react with rat, dog and cow based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Octamer-binding transcription factor EMB; POU domain, class 6, transcription factor 1; Transcription regulatory protein MCP-1
基因别名: 2310038G18Rik; C79593; cns-1; Emb; Pou6f1
UniProt ID: (Mouse) Q07916
Entrez Gene ID: (Mouse) 19009