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Proteintech
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Immunogen sequence: MAAERGAGQ QQSQEMMEVD RRVESEESGD EEGKKHSSGI VADLSEQSLK DGEERGEEDP EEEHELPVDM ETINLDRDAE DVDLNHYRIG KIEGFEVLKK VKTLCLRQNL IKCIENLEEL QSLRELDLYD NQIKKIENLE ALTELEILDI SFNLLRNIEG VDKLTRLKKL FLVNNKISKI ENLSNLHQLQ MLELGSNRIR AIENIDTLTN LESLFLGKNK ITKLQNLDAL TNLTVLSMQS NRLTKIEGLQ NLVNLRELYL SHNGIEVIEG LENNNKLTML DIASNRIKKI ENISHLTELQ EFWMNDNLLE SWSDLDELKG ARSLETVYLE RNPLQKDPQY RRKVMLALPS VRQIDATFVR F (1-360 aa encoded by BC000910)
In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase 1 (PP1) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit, and a catalytic subunit. Sds22, also known as PPP1R7 (protein phosphatase 1, regulatory (inhibitor) subunit 7), is a 360 amino acid protein that localizes to the nucleus and contains ten LRR (leucine rich) repeats. Expressed in a variety of tissues, Sds22 functions as a regulatory subunit of the PP1 complex, suggesting a role in protein regulation throughout the cell. Multiple isoforms of Sds22 exist due to alternative splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein phosphatase 1 regulatory subunit 22; Protein phosphatase 1 regulatory subunit 7; protein phosphatase 1, regulatory (inhibitor) subunit 7; protein phosphatase 1, regulatory subunit 7; protein phosphatase-1 regulatory subunit 7; testis secretory sperm-binding protein Li 210a
基因别名: 2310014J01Rik; PPP1R7; SDS22
UniProt ID: (Human) Q15435, (Mouse) Q3UM45
Entrez Gene ID: (Human) 5510, (Mouse) 66385