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Proteintech
PPP2CB Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
12554-2-AP
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PPP2CB Fusion Protein Ag3233 (1-309 aa encoded by BC012022)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDDKAFTKE LDQWVEQLNE CKQLNENQVR TLCEKAKEIL TKESNVQEVR CPVTVCGDVH GQFHDLMELF RIGGKSPDTN YLFMGDYVDR GYYSVETVTL LVALKVRYPE RITILRGNHE SRQITQVYGF YDECLRKYGN ANVWKYFTDL FDYLPLTALV DGQIFCLHGG LSPSIDTLDH IRALDRLQEV PHEGPMCDLL WSDPDDRGGW GISPRGAGYT FGQDISETFN HANGLTLVSR AHQLVMEGYN WCHDRNVVTI FSAPNYCYRC GNQAAIMELD DTLKYSFLQF DPAPRRGEPH VTRRTPDYFL (1-309 aa encoded by BC012022)
靶标信息
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: phosphatase 2A; PP2A beta; PP2A-beta; PP2Abeta; PP2CB; PPP2bc; PPP2CB; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2A catalytic alpha subunit; protein phosphatase 2A-beta catalytic subunit; protein phosphatase type 2A catalytic subunit; protein phosphatase-2A-beta; testicular tissue protein Li 146; unnamed protein product
基因别名: D8Ertd766e; Pp2a2; PP2Abeta; PP2Ac; PP2CB
UniProt ID: (Human) P62714, (Mouse) P62715, (Rat) P62716
Entrez Gene ID: (Human) 5516, (Mouse) 19053, (Rat) 24673
mitotic cell cycle
protein dephosphorylation
apoptotic mitochondrial changes
response to lead ion
regulation of gene expression
negative regulation of gene expression
negative regulation of tumor necrosis factor-mediated signaling pathway
regulation of microtubule polymerization
response to endoplasmic reticulum stress
response to hydrogen peroxide
negative regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of Ras protein signal transduction
response to antibiotic
regulation of neurofibrillary tangle assembly
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