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Proteintech
PPP2R1A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
15882-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PPP2R1A Fusion Protein Ag8661 (239-589 aa encoded by BC001537)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.16 mg/mL
规格
24 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: DLEALVMPT LRQAAEDKSW RVRYMVADKF TELQKAVGPE ITKTDLVPAF QNLMKDCEAE VRAAASHKVK EFCENLSADC RENVIMSQIL PCIKELVSDA NQHVKSALAS VIMGLSPILG KDNTIEHLLP LFLAQLKDEC PEVRLNIISN LDCVNEVIGI RQLSQSLLPA IVELAEDAKW RVRLAIIEYM PLLAGQLGVE FFDEKLNSLC MAWLVDHVYA IREAATSNLK KLVEKFGKEW AHATIIPKVL AMSGDPNYLH RMTTLFCINV LSEVCGQDIT TKHMLPTVLR MAGDPVANVR FNVAKSLQKI GPILDNSTLQ SEVKPILEKL TQDQDVDVKY FAQEALTVLS LA (239-589 aa encoded by BC001537)
靶标信息
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: medium tumor antigen-associated 61 KDA protein; MGC786; PP2Ac; PP2CA; PP2Calpha; PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; protein phosphatase PP2A; RP-C; serine/threonine protein phosphatase A subunit type 2A; testicular secretory protein Li 1; unnamed protein product
基因别名: 6330556D22Rik; HJS2; MRD36; PP2A; PP2A-Aalpha; PP2AA; PP2AAALPHA; PR65; PR65A
UniProt ID: (Human) P30153, (Mouse) Q76MZ3
Entrez Gene ID: (Human) 5518, (Mouse) 51792, (Rat) 117281
chromosome segregation
snRNA processing
regulation of transcription elongation from RNA polymerase II promoter
regulation of hippo signaling
negative regulation of hippo signaling
intracellular signal transduction
regulation of growth
T cell homeostasis
regulation of cell differentiation
spindle assembly
meiotic sister chromatid cohesion, centromeric
negative regulation of protein kinase B signaling
protein-containing complex assembly
RNA polymerase II transcription initiation surveillance
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
female meiotic division
meiotic spindle elongation
mitotic sister chromatid separation
peptidyl-serine dephosphorylation
regulation of meiotic cell cycle process involved in oocyte maturation
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
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