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Invitrogen
PPP2R1A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-17516
产品规格
种属反应
Fruit fly,
Human,
Mouse,
Non-human primate,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the carboxy terminus of human PP2A A subunit
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
33 µg/mL
规格
3.3 µg
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other PP2A subunits.
靶标信息
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Upon interaction with GNA12 promotes dephosphorylation of microtubule associated protein TAU/MAPT. Required for proper chromosome segregation and for centromeric localization of SGO1 in mitosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 65 kDa regulatory subunit of protein phosphatase; alpha isoform of regulatory subunit A, protein phosphatase 2; CG17291-PA; CG17291-PB; CG17291-PC; CG17291-PD; CG17291-PE; Medium tumor antigen-associated 61 kDa protein; MGC786; PP2A 65kD subunit A; PP2A subunit A isoform PR65-alpha; PP2A subunit A isoform R1-alpha; Pp2A-29B-PA; Pp2A-29B-PB; Pp2A-29B-PC; Pp2A-29B-PD; Pp2A-29B-PE; PP2Aa; PP2Ac; PP2CA; PP2Calpha; PR65; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform; protein phosphatase 2A; protein phosphatase PP2A; Protein phosphatase PP2A regulatory subunit A; protein phosphate 2A; regulatory subunit A of type 2A protein phosphatase; RP-C; serine/threonine protein phosphatase A subunit type 2A; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform; Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit
基因别名: 29B; 6330556D22Rik; A/PR65; CG13383; CG17291; CG33297; Dmel\CG17291; Dmel_CG17291; dPP2A A; DPR65; PP2A; PP2A 29B; PP2A A; PP2A-29B; PP2A-A; Pp2A29B; PP2A[A]; PPP2R1A; PR65
UniProt ID: (Fruit fly) P36179, (Mouse) Q76MZ3
Entrez Gene ID: (Fruit fly) 2768940, (Mouse) 51792, (Rat) 117281
protein dephosphorylation
autophagy
chromosome segregation
centrosome cycle
centriole replication
negative regulation of hippo signaling
negative regulation of smoothened signaling pathway
negative regulation of insulin receptor signaling pathway
spindle assembly
female meiotic division
meiotic spindle elongation
mitotic sister chromatid separation
meiotic sister chromatid cohesion, centromeric
peptidyl-serine dephosphorylation
regulation of meiotic cell cycle process involved in oocyte maturation
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
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