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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAHHLPAAME NHQDFRSIKA KFQASQPEPS DLPKKPPKPE FGKLKKFSQP ELSEHPKKAP LPEFGAVSLK PPPPEVTDLP KKPPPPEVTD LPKKPPPPEV TDLPKKPPPP EVTDLPKKPS KLELSDLSKK FPQLGATPFP RKPLQPEVGE APLKASLPEP GAPARKPLQP DELSHPARPP SEPKSGAFPR KLWQPEAGEA TPRSPQPELS TFPKKPAQPE FNVYPKKPPQ PQVGGLPKKS VPQPEFSEAA QTPLWKPQSS EPKRDSSAFP KKASQPPLSD FPKKPPQPEL GDLTRTSSEP EVSVLPKRPR PAEFKALSKK PPQPELGGLP RTSSEPEFNS LPRKLLQPER RGPPRKFSQP EPSAVLKRHP QPEFFGDLPR KPPLPSSASE SSLPAAVAGF SSRHPLSPGF GAAGTPRWRS GGLVHSGGAR PGLRPSHPPR RRPLPPASSL GHPPAKPPLP PGPVDMQSFR RPSAASIDLR RTRSAAGLHF QDRQPEDIPQ VPDEIYELYD DVEPRDDSSP SPKGRDEAPS VQQAARRPPQ DPALRKEKDP QPQQLPPMDP KLLKQLRKAE KAEREFRKKF KFEGEIVVHT KMMIDPNAKT RRGGGKHLGI RRGEILEVIE FTSNEEMLCR DPKGKYGYVP RTALLPLETE VYDDVDFCDP LENQPLPLGR
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC39864; PML-RARA target gene encoding an Adaptor Molecule-1; PRAM; PRAM-1 protein
基因别名: PML-RAR; PRAM-1
UniProt ID: (Human) Q96QH2
Entrez Gene ID: (Human) 84106