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Abnova
PRG4 Monoclonal Antibody (1D5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00010216-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1D5
抗原
PRG4 (NP_005798, 1305 a.a. approximately 1404 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.21 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: ERAIGPSQTH TIRIQYSPAR LAYQDKGVLH NEVKVSILWR GLPNVVTSAI SLPNIRKPDG YDYYAFSKDQ YYNIDVPSRT ARAITTRSGQ TLSKVWYNCP
靶标信息
Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: articular superficial zone protein; hemangiopoietin; lubricin; megakaryocyte stimulating factor; Proteoglycan-4; superficial zone proteoglycan; unnamed protein product
基因别名: CACP; HAPO; JCAP; MSF; SZP
UniProt ID: (Human) Q92954
Entrez Gene ID: (Human) 10216
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