Search
Abnova
PRKAA1 Monoclonal Antibody (3B6)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00005562-M04
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3B6
抗原
PRKAA1 (AAH12622, 451 a.a. approximately 550 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: LQLYQVDSRT YLLDFRSIDD EITEAKSGTA TPQRSGSVSN YRSCQRSDSD AEAQGKSSEV SLTSSVTSLD SSPVDLTPRP GSHTIEFFEM CANLIKILAQ
靶标信息
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 5'-AMP-activated protein kinase, catalytic alpha-1 chain; AAPK2; ACACA kinase; acetyl-CoA carboxylase kinase; activated protein kinase; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, catalytic, alpha-1; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK, alpha, 1; AMPK-alpha-2 chain; AMPK2; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; PRKAA2; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1; unnamed protein product
基因别名: AMPK; AMPK alpha 1; AMPKa1
UniProt ID: (Human) Q13131
Entrez Gene ID: (Human) 5562
chromatin binding
protein kinase activity
protein serine/threonine kinase activity
AMP-activated protein kinase activity
cAMP-dependent protein kinase activity
protein binding
ATP binding
macromolecular complex binding
[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity
tau protein binding
tau-protein kinase activity
protein serine kinase activity
histone H2BS36 kinase activity
response to hypoxia
positive regulation of T cell mediated immune response to tumor cell
chromatin remodeling
signal transduction
positive regulation of cell proliferation
lipid biosynthetic process
cellular response to starvation
response to xenobiotic stimulus
response to UV
cold acclimation
response to gamma radiation
positive regulation of autophagy
negative regulation of gene expression
response to activity
response to caffeine
cellular response to nutrient levels
negative regulation of TOR signaling
cellular response to stress
cellular response to oxidative stress
cellular response to glucose starvation
response to hydrogen peroxide
glucose homeostasis
regulation of circadian rhythm
negative regulation of apoptotic process
regulation of vascular permeability
response to estrogen
positive regulation of cholesterol biosynthetic process
positive regulation of glycolytic process
positive regulation of transcription, DNA-templated
negative regulation of glucosylceramide biosynthetic process
negative regulation of insulin receptor signaling pathway
positive regulation of T cell activation
negative regulation of lipid catabolic process
fatty acid homeostasis
regulation of vesicle-mediated transport
motor behavior
CAMKK-AMPK signaling cascade
regulation of stress granule assembly
neuron cellular homeostasis
cellular response to hydrogen peroxide
regulation of microtubule cytoskeleton organization
cellular response to calcium ion
cellular response to glucose stimulus
cellular response to ethanol
cellular response to hypoxia
cellular response to xenobiotic stimulus
protein localization to membrane
protein localization to plasma membrane
energy homeostasis
negative regulation of ferroptosis
positive regulation of transcription from mitochondrial promoter
positive regulation of establishment of protein localization to mitochondrion
positive regulation of cellular protein localization
negative regulation of hepatocyte apoptotic process
positive regulation of adipose tissue development
negative regulation of TORC1 signaling
lipid droplet disassembly
protein localization to lipid particle
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
