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Invitrogen
PRKAR2A Monoclonal Antibody (RS6)
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产品信息
MA1-20071
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
RS6
抗原
Purified regulatory subunit of cAMP-dependent protein kinase type II from bovine brain.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
产品详细信息
MA1-20071 detects PRKAR2 in human, bovine and porcine samples.
MA1-20071 has been successfully used in ELISA and immunofluorescence procedures.
The MA1-20071 immunogen is purified regulatory subunit of cAMP-dependent protein kinase type II from bovine brain.
靶标信息
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase (AMPK), which transduces the signal through phosphorylation of different target proteins. The inactive holoenzyme of AMPK is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits of AMPK have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of AMPK.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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