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Proteintech
PRKX/PRKY Polyclonal Antibody
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产品信息
17985-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PRKX/PRKY fusion protein Ag12404
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: MEAPGPAQAA AAESNSREVT EDAADWAPAL CPSPEARSPE APAYRLQDCD ALVTMGTGTF GRVHLVKEKT AKHFFALKVM SIPDVIRRKQ EQHVHNEKSV LKEVSHPFLI RLFWTWHEER FLYMLMEYVP GGELFSYLRN RGHFSSTTGL FYSAEIICAI EYLHSKEIVY RDLKPENILL DRDGHIKLTD FGFAKKLVDR TWTLCGTPEY LAPEVIQSKG HGRAVDWWAL GILIFEMLSG FPPFFDDNPF GIYQKILAGK LYFPRHLDFH VKTGRMM
靶标信息
PRKY is a member of the cAMP-dependent serine-threonine protein kinase gene family, which appears to encode a protein related to the catalytic subunit of the cAMP-dependent protein kinases, which are key players in the cellular responses to the second messenger cAMP. A chromosomal aberration involving PRKY is a cause of sex reversal disorder. PRKX is a serine/threonine kinase related to the catalytic subunit of the cAMP-dependent protein kinases. PRKX is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y.
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生物信息学
蛋白别名: cAMP-dependent protein kinase catalytic subunit PRKX; PKA-related protein kinase; PrKX; Protein kinase PKX1; protein kinase X; protein kinase X-linked; putative serine/threonine kinase; serine/threonine-protein kinase PRKX
基因别名: Pkare; PKX1; PRKX; PRKXP3; PRKYP
UniProt ID: (Human) P51817, (Mouse) Q922R0
Entrez Gene ID: (Human) 5613, (Human) 5616, (Mouse) 19108
angiogenesis
endothelial cell proliferation
cell adhesion
peptidyl-serine phosphorylation
myeloid cell differentiation
regulation of cell adhesion
regulation of cell migration
cell-substrate adhesion
endothelial cell migration
protein autophosphorylation
epithelial tube morphogenesis
kidney morphogenesis
regulation of epithelial cell differentiation involved in kidney development
protein phosphorylation
multicellular organism development
phosphorylation
cell differentiation
