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Invitrogen
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Additional Information: This antibody is expected to recognize isoform a (NP_001119600.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.
Preliminary analysis showed no signal in Western Blot.
Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: PK2; Prokineticin-2; Protein Bv8 homolog
基因别名: BV8; HH4; KAL4; MIT1; PK2; PROK2
UniProt ID: (Human) Q9HC23
Entrez Gene ID: (Human) 60675