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Invitrogen
PROK2 Polyclonal Antibody
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产品信息
PA5-59557
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human PROK2
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: TCPCLPGLAC LRTSFNRFIC LAQ
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
靶标信息
Prokineticin-2 (PK2) is a cysteine-rich secreted protein that is expressed in the suprachiasmatic nucleus (SCN) with receptors located in the critical autonomic control centers of the brain. It has a depolarizing effect on neurons expressing the receptor. PK2 is predominantly controlled by the endogenous circadian clock, but light also plays a modulatory role. PK2 functions as a critical SCN output molecule responsible for circadian locomotor rhythms. PK2 expression is high during the day, and responsive to nocturnal light pulses. PK2 also functions as a chemoattractant for subventricular zone-derived neuronal progenitors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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