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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. A suggested positive control for immunohistochemical applications is human prostate.
Sheep anti Human prostate specific antigen antibody recognizes human prostate specific antigen, a 33-34 kDa glycoprotein with chymotrypsin-like protease activity.
PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Antigen; Gamma-seminoprotein; Kallikrein 3; Kallikrein-3; Kallikrein-3 (KLK3); KLK-3; P-30 antigen; prostate-specific (APS); Prostate-specific antigen; PSA; Semenogelase; Seminin
基因别名: APS; KLK3
Entrez Gene ID: (Human) 354