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Invitrogen
PSCA Polyclonal Antibody
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PSCA Antibody (PA5-75178) in WB
Western blot analysis of PSCA in Lane 1: HeLa whole cell lysate (40 µg), Lane 2: PC3 whole cell lysate (40 µg), Lane 3: CT26 whole cell lysate (40 µg), Lane 4: PC12 whole cell lysate (40 µg). Samples were incubated with PSCA polyclonal antibody (Product # PA5-75178) at a dilution of 1:500.
产品信息
PA5-75178
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 41-90 of Human PSCA.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: caldesmon; CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22; Prostate stem cell antigen; UNQ206
基因别名: 2210408B04Rik; PRO232; PSCA; UNQ206/PRO232
UniProt ID: (Human) O43653, (Mouse) P57096
Entrez Gene ID: (Human) 8000, (Mouse) 72373
