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Proteintech
PSMC1 Polyclonal Antibody
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产品信息
11196-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PSMC1 Fusion Protein Ag1677 (77-440 aa encoded by BC016368)
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EFIRNQEQM KPLEEKQEEE RSKVDDLRGT PMSVGTLEEI IDDNRAIVST SVGSEHYVSI LSFVDKDLLE PGCSVLLNHK VHAVIGVLMD DTDPLVTVMK VEKAPQETYA DIGGLDNQIQ EIKESVELPL THPEYYEEMG IKPPKGVILY GPPGTGKTLL AKAVANQTSA TFLRVVGSEL IQKYLGDGPK LVRELFRVAE EHAPSIVFID EIDAIGTKRY DSNSGGEREI QRTMLELLNQ LDGFDSRGDV KVIMATNRIE TLDPALIRPG RIDRKIEFPL PDEKTKKRIF QIHTSRMTLA DDVTLDDLIM AKDDLSGADI KAICTEAGLM ALRERRMKVT NEDFKKSKEN VLYKKQEGTP EGLYL (77-440 aa encoded by B C016368)
靶标信息
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 26S protease regulatory subunit 4; 26S proteasome AAA-ATPase subunit RPT2; 26S proteasome regulatory subunit 4; MGC24583; MGC8541; P26s4; peptidase (prosome, macropain) 26S subunit, ATPase 1; protease (prosome, macropain) 26S subunit, ATPase 1; proteasome (prosome, macropain) 26S subunit, ATPase, 1; proteasome 26S ATPase subunit 1; Proteasome 26S subunit ATPase 1; proteasome 26S subunit, ATPase, 1; prs4
基因别名: AI325227; P26S4; p56; PSMC1; rpt2; Rpt2/S4; S4
UniProt ID: (Human) P62191, (Rat) P62193, (Mouse) P62192
Entrez Gene ID: (Human) 5700, (Rat) 117263, (Mouse) 19179
MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
negative regulation of neuron death
positive regulation of proteasomal protein catabolic process
biological_process
protein catabolic process
