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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MYEQLKGEWN RKSPNLSKCG EELGRLKLVL LELNFLPTTG TKLTKQQLIL ARDILEIGAQ WSILRKDIPS FERYMAQLKC YYFDYKEQLP ESAYMHQLLG LNLLFLLSQN RVAEFHTELE RLPAKDIQTN VYIKHPVSLE QYLMEGSYNK VFLAKGNIPA ESYTFFIDIL LDTIRDEIAG CIEKAYEKIL FTEATRILFF NTPKKMTDYA KKRGWVLGPN NYYSFASQQQ KPEDTTIPST ELAKQVIEYA RQLEMIV
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 26S proteasome regulatory subunit p31; 26S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; epididymis secretory sperm binding protein Li 91n; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8; unnamed protein product
基因别名: HEL-S-91n; HIP6; HYPF; Nin1p; p31; Rpn12; S14
UniProt ID: (Human) P48556
Entrez Gene ID: (Human) 5714