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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
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Immunogen sequence: AYYGAFKDVK EKNRTSEEAE DLRAL
Highest antigen sequence indentity to the following orthologs: Rat - 56%, Mouse - 52%.
The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dp receptor; MGC49004; PGD2 receptor; PTGDR
基因别名: AS1; ASRT1; DP; DP1; PTGDR1
UniProt ID: (Human) Q13258
Entrez Gene ID: (Human) 5729