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Invitrogen
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Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Monkey (95%) Gibbon (89%).
The protein encoded by this gene is a G-protein-coupled receptor. It has been shown to function as a prostanoid DP receptor. The activity of this receptor is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。