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Invitrogen
PTPN23 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-53504
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VLDQFMDSMQ LDPETVDNLD AYSHIPPQLM EKCAALSVRP DTVRNLVQSM QVLSGVFTDV EASLKDIRDL LEEDELLEQK FQEAVGQAGA ISITSKAELA EVRREWAKYM EVHEKASFTN SELHRAMNLH VGN
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
靶标信息
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: his domain-containing protein tyrosine phosphatase; protein tyrosine phosphatase TD14; PTP-TD14; unnamed protein product
基因别名: HD-PTP; HDPTP; NEDBASS; PTP-TD14
UniProt ID: (Human) Q9H3S7
Entrez Gene ID: (Human) 25930
negative regulation of epithelial cell migration
endocytic recycling
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
early endosome to late endosome transport
cilium morphogenesis
positive regulation of Wnt protein secretion
positive regulation of homophilic cell adhesion
positive regulation of adherens junction organization
positive regulation of early endosome to late endosome transport
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