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Recommended positive controls: HeLa.
Predicted reactivity: Mouse (80%), Rat (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. The extracellular region contains eight fibronectin type III-like repeats and multiple N-glycosylation sites. The gene was shown to be expressed primarily in brain and liver, and at a lower level in heart and stomach. It was also found to be expressed in several cancer cell lines, but not in the corresponding normal tissues.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: brain-enriched membrane-associated protein tyrosine BEM-2; protein tyrosine phosphatase, receptor type, H; R-PTP-H; Receptor-type tyrosine-protein phosphatase H; SAP-1; Stomach cancer-associated protein tyrosine phosphatase 1; Transmembrane-type protein-tyrosine phosphatase type H
基因别名: Bem2; PTPRH; R-PTP-H; SAP1
UniProt ID: (Human) Q9HD43
Entrez Gene ID: (Human) 5794, (Rat) 171125