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Invitrogen
PTPRO Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-56964
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TRVNISYWEG KDFRTMLYKD FFKGKTVFNH WLPGMCYSNI TFQLVSEATF NKSTLVEYSG VSHEPKQHRT APYPPQNISV RIVNLNKNNW EEQSGNFPEE SFMRSQDTIG KEKLFHFTEE TPEIPSGNIS SGWP
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.
靶标信息
Glomerular epithelial protein 1 (GLEPP1), also designated protein tyrosine phosphatase U2 (PTPase U2) or receptor-type tyrosine-protein phosphatase O (PTPRO), belongs to the protein-tyrosine phosphatase family. GLEPP1 is a Type I membrane protein containing 8 fibronectin type-III domains and 1 tyrosine-protein phosphatase domain. GLEPP1 is expressed primarily in the glomeruli of the kidney, but is also detected in placenta, lung and brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FMI; glomerular epithelial protein 1; hPTP-J; osteoclastic transmembrane protein-tyrosine phosphatase; PCP-2; PCP2; phosphotyrosine phosphatase U2; protein tyrosine phosphatase PTP-U2; PTP phi; PTP pi; PTP-J; PTP-RO; PTPase U2; PTPRU; R-PTP-psi; R-PTP-U; unnamed protein product
基因别名: GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPROT; PTPU2; R-PTP-O
UniProt ID: (Human) Q16827
Entrez Gene ID: (Human) 5800
cell morphogenesis
monocyte chemotaxis
regulation of glomerular filtration
negative regulation of glomerular filtration
axon guidance
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
lamellipodium assembly
glomerulus development
slit diaphragm assembly
regulation of synapse organization
glomerular visceral epithelial cell differentiation
negative regulation of canonical Wnt signaling pathway
negative regulation of retinal ganglion cell axon guidance
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
