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Abnova
PXDN Monoclonal Antibody (2C11)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00007837-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2C11
抗原
PXDN (XP_056455, 1452 a.a. approximately 1561 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.48 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: STSAFSTRSD ASGTNDFREF VLEMQKTITD LRTQIKKLES RLSTTECVDA GGESHANNTK WKKDACTICE CKDGQVTCFV EACPPATCAV PVNIPGACCP VCLQKRAEEK
靶标信息
Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: animal heme peroxidase; KIAA0230; melanoma-associated antigen MG50; p53-responsive gene 2 protein; peroxidasin 1; vascular peroxidase 1
基因别名: ASGD7; COPOA; D2S448; D2S448E; hsPxd01; MG50; PRG2; PXN; VPO
UniProt ID: (Human) Q92626
Entrez Gene ID: (Human) 7837
angiogenesis
eye development
negative regulation of cytokine-mediated signaling pathway
immune response
response to oxidative stress
cell adhesion
extracellular matrix organization
collagen fibril organization
hydrogen peroxide catabolic process
system development
protein homooligomerization
protein homotrimerization
basement membrane assembly
basement membrane organization
cellular oxidant detoxification
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
