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GenScript
Pembrolizumab Recombinant Rabbit Monoclonal Antibody (90G12), Biotin, MonoRab™
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Pembrolizumab Antibody (A01853-40) in ELISA
MonoRab™ Anti-Pembrolizumab antibody (90G12) (GenScript, A01853-40) blocks Pembrolizumab binding with Human PD-1 recombinant protein (Z03370, PD 1-Fc Chimera, Human). Coating antigen: Pembrolizumab, 1 µg/mL. PD 1-Fc-biotin final concentration: 20 ng/mL. Anti-Pembrolizumab antibody (GenScript, A01853-40) dilution start from 10 µg/mL. IC50 = 0.38 µg/mL.
产品信息
A01853-40
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Mammalian cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
90G12
抗原
Pembrolizumab
偶联物
形式
Lyophilized
纯化类型
Protein A
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Pembrolizumab(Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Foodand Drug Administration for the treatment of patients with unresectable ormetastatic melanoma. Pembrolizumab binds to the human cell surface receptorPD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1,resulting in the activation of T-cell-mediated immune responses against tumorcells.GenScript MonoRab™ Anti-PembrolizumabAntibody (90G12F8) [Biotin], mAb, Rabbit is produced from ahybridoma resulting from the fusion of partner and B-lymphocytes obtained froma rabbit immunized with Pembrolizumab.
Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below.
靶标信息
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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