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Invitrogen
Pentachloronitrobenzene Recombinant Mouse Monoclonal Antibody (2F5)
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Pentachloronitrobenzene Antibody (MA566373) in SDS-PAGE
SDS-PAGE characterization of Pentachloronitrobenzene under reducing conditions. Lane M: Protein marker (kDa); Lane PCNB: Purified Pentachloronitrobenzene Recombinant Monoclonal (Product # MA566373). Pentachloronitrobenzene showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-647.
产品信息
MA566373
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2F5
抗原
Conjugate of PCNB hapten and KLH.
偶联物
形式
Liquid
浓度
3.8 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Pentachloronitrobenzene (PCNB) is a hexa-substituted benzene compound characterized by a benzene ring with a nitro group (-NO2) and five chlorine atoms. It exhibits a quasi-planar structure and forms a layered rhombohedral configuration below its melting point, allowing molecular rotation around a six-fold axis. PCNB is primarily used as an organochlorine fungicide with broad antifungal activity, similar to chlorothalonil, by inhibiting fungal enzymes such as cytochrome reductase through electrophilic interaction with thiol groups. It is persistent in soils due to its high chemical stability, leading to bioaccumulation in plants, which poses risks to food safety and human health. PCNB's fungicidal activities have been tested against various fungi, including Candida albicans and Aspergillus fumigatus, although derivatives like pentachlorophenylmethylsulfone show increased fungistatic activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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