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Invitrogen
Phospho-CrkII (Tyr221) Polyclonal Antibody
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产品信息
PA5-35641
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from human CrkII around the phosphorylation site of Tyrosine 221
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
-20°C
运输条件
Ambient
RRID
产品详细信息
Concentration is lot-specific and will vary from 0.5-0.6 mg/ml
靶标信息
The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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