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Invitrogen
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PA1-26729 detects Phospho-Dab1 pSer491 from human and mouse samples. PA1-26729 is expected to cross react with chicken (100% conserved) and rat (100% conserved) due to sequence homology.
PA1-26729 has been successfully used in Western blot procedures.
The PA1-26729 immunogen is a synthetic phosphopeptide corresponding to a portion of human Dab1 containing serine 491.
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。