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Invitrogen
Phospho-Dopamine Transporter (Thr53) Polyclonal Antibody
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Phospho-Dopamine Transporter (Thr53) Antibody (PA5-35414) in WB
Western blot of Dopamine Transporter in rat striatal lysate showing specific immunolabeling of a band at ~55 kDa corresponding to glycosylated form of the Phospho-Dopamine Transporter (Thr53) polyclonal antibody (Product # PA5-35414) in the first lane (-). Phosphospecificity is shown in the second lane (+) where immunolabeling is blocked by pre-adsorption of the phosphopeptide used as the antigen, but not b... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-35414
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr53 of rat SLC6A3 conjugated to KLH
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.25 mg/mL
规格
25 µg
纯化类型
Affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.1mg/mL BSA, 50% glycerol, 0.15M NaCl
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody contains enough material to conduct 10 mini-Western blots. Relative mobility may vary depending on the state of glycosylation of the DAT protein. The antibody works best in lysates that have not been boiled prior to being run on an SDS-PAGE gel.
靶标信息
The Dopamine Transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DA transporter; DAT; dopamine transporter 1; solute carrier family 6 (neurotransmitter transporter), member 3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; unnamed protein product
基因别名: DAT; Dat1
UniProt ID: (Mouse) Q61327, (Rat) P23977
Entrez Gene ID: (Mouse) 13162, (Rat) 24898
protease binding
receptor binding
neurotransmitter transporter activity
dopamine:sodium symporter activity
norepinephrine:sodium symporter activity
protein binding
monoamine transmembrane transporter activity
dopamine binding
amine binding
macromolecular complex binding
protein phosphatase 2A binding
heterocyclic compound binding
neurotransmitter uptake
neurotransmitter transport
amino acid transport
lactation
sensory perception of smell
locomotory behavior
response to xenobiotic stimulus
response to iron ion
adenohypophysis development
response to nicotine
sodium ion transmembrane transport
positive regulation of multicellular organism growth
regulation of dopamine metabolic process
response to cocaine
dopamine biosynthetic process
dopamine catabolic process
response to leptin
response to ethanol
cognition
dopamine uptake involved in synaptic transmission
response to cAMP
norepinephrine uptake
prepulse inhibition
dopamine uptake
hyaloid vascular plexus regression
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
