Invitrogen

Phospho-Histone H4 (Tyr72) Polyclonal Antibody

Name: Phospho-Histone H4 (Tyr72) Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-143708

查看其他51个Histone H4抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)

Phospho-Histone H4 (Tyr72) Antibody in Western Blot (WB)

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Phospho-Histone H4 (Tyr72) Antibody (PA5-143708) in WB

Western blot of Phospho-Histone H4 (Tyr72) in human PC3 cells untreated (lanes 1 & 3) or treated with alkaline phosphatase to dephosphorylate histone H4 (lanes 2 and 4). The blot was probed with rabbit anti-Histone H4 polyclonal (lanes 1 & 2) and Phospho-Histone H4 (Tyr72) polyclonal antibody (Product # PA5-143708) (lanes 3 & 4).

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产品信息

PA5-143708

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Phospho-Histone H4 (Tyr-72) synthetic peptide (coupled to carrier) corresponding to amino acids surrounding Tyr-72 in human histone H4. This site is well conserved in rat and mouse histone H4, but the site is not found in other histone family members.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS with 1mg/mL BSA, 50% glycerol

内含物

0.05% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2942936

产品详细信息

The antibody was cross adsorbed to unphosphorylated histone H4 (Tyr-72) peptide before affinity purification using phospho-histone H4 (Tyr-72) peptide. This antibody antibody detects a 10 kDa* protein on SDS-PAGE immunoblots of human PC3 and A431 cells. This reactivity is not observed after alkaline phosphatase dephosphorylation of histone H4.

靶标信息

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: H4 histone family, member A; H4 histone family, member E; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 1, H4j; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; Histone Cluster 4; histone family member; Histone H4; Histone H4A; histone IV, family 2

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基因别名: dJ160A22.2; FO108; H4; H4-12; H4-16; H4-53; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4f16; H4F2; H4F2iv; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; HIST2H4; HIST2H4A; HIST2H4B; HIST4H4; X04652

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UniProt ID: (Human) P62805, (Mouse) P62806, (Mouse) A4QMY0